Iox2?

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Question: Iox2?

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IOX2 is a selective inhibitor of the hypoxia inducible factor (HIF) prolyl-hydroxylases (PHD) that exhibits up-regulation of HIF1a in zebrafish. IOX2: A chemical probe for HIF prolyl-hydroxylases. IOX2 potently inhibits PHD2 (IC50 = 21 nM) with over 100-fold selectivity compared to inhibition of JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH. View and buy high purity IOX 2 from Tocris Bioscience.

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Answered By:
Joseph

Joseph

Vijayawada, India

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