Isabella Astin

In this blog we’ll give you a quick overview on AMPK, the benefits of activating it and how you can naturally boost your levels to reap its benefits.

What is AMP-Activated Protein Kinase (AMPK)

AMPK, short for adenosine monophosphate activated protein kinase, is an enzyme found in our cells that plays a critical role in energy metabolism. Think of it as a master switch turning on and off as it regulates energy intake and energy expenditure. When our energy levels become low (e.g. exercise, stress, hunger), that is when AMPK is activated to help restore balance to our cells. Although its primary role is in energy metabolism it is becoming more clear that AMPK has even more benefits at the cellular level.

Benefits of AMPK

There are numerous benefits that come with activating AMPK:

Lifestyle and Dietary Habits that Can Increase the Levels of AMPK

Boost the Intensity of Your Workouts: High intensity exercise depletes ATP and activates AMPK. This promotes new mitochondria (where ATP is made) and also helps to repair any damage that results from the intensity of the workout

Bump Up Your Intake of Dietary Fiber: Studies have shown that water-soluble, dietary fiber (think oatmeal and apples) can enhance AMPK. This can aid in weight loss and improve lipid and glucose profiles.

Curb Your Calories: Eating fewer calories makes fat cells release a hormone called adiponectin which activates AMPK in different tissues. Calorie restriction has been shown to minimize the risk for disease and slow down the aging process. This is the foundation of the Zone Diet.

Watch Your Carbs: Consuming too many carbohydrates in your diet can spike the levels of a hormone call insulin. If uncontrolled, high levels of insulin over the long-term can lead to insulin resistance which has been shown to decrease AMPK levels

Minimize Inflammation: High levels of inflammation directly inhibit AMPK activation. Foods rich in omega3s like fish and fish oil can help reduce this inflammation. Omega-3 have also been shown to increase the hormone adiponectin which activates AMPK.

Get Your Polyphenols: Non-starchy vegetables and fruits are rich in polyphenols (and fiber!). Polyphenols are the chemicals that give fruits and vegetables their color, and can help activate AMPK.

Lifestyle and Dietary Habits that Can Decrease the Levels of AMPK

Here are some of dietary factors that can work against activating AMPK.

Excess calorie intake:  Eating too many calories immediately shuts down AMPK.  Try to keep intake at any one meal to about 400 calories.

Excess glucose intake:  The vast majority of glucose in the diet comes from grains and starches. Consuming carbohydrate rich foods like these stops AMPK activity by increasing insulin, a hormone used to control blood sugar levels.

Insulin resistance:  When our bodies don’t respond properly to insulin it can build up in our blood and lead to a condition called insulin resistance. Elevated insulin levels are powerful inhibitor of AMPK.

Ketogenic diets: Ketogenic diets, low carbohydrate, high fat dietary, have recently been linked to insulin resistance, an inhibitor of AMPK, and a risk factor for type 2 diabetes. Following a ketogenic diet makes our body not respond appropriately to insulin.

Summary

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STUTTGART, Germany, Nov. 16, 2022 /PRNewswire/ -- Exyte, a global leader in the design, engineering, and delivery of high-tech facilities, has announced that funds affiliated with BDT Capital Partners, LLC ("BDT") have entered into an agreement to acquire a significant minority interest in Exyte. BDT, a merchant bank that provides advice and long-term capital through its affiliated funds to help family- and founder-led businesses pursue their strategic and financial objectives, will become a minority shareholder of Exyte alongside Georg Stumpf, Exyte's current sole owner who will retain a majority stake.

Don McLellan, Partner at BDT says, "Exyte is a leader in the design, development, and delivery of the world's most sophisticated manufacturing environments. The company plays an indispensable role enabling clients across semiconductor, biopharma, life sciences, and cloud computing industries to create best-in-class facilities where technological breakthroughs happen. Due to the strong leadership of Exyte's management team and the dedication of its talented employees in serving the needs of its clients, the company has an impressive track record of profitable growth. We look forward to partnering with Georg Stumpf and the Exyte management team to help continue and enhance the company's growth and impact."

Georg Stumpf, Exyte's continuing majority shareholder, says: "Exyte serves the most technically demanding customers in thriving markets. The company is a driving force behind important megatrends of today and tomorrow, as well as developments that will profoundly change individual and societal life and promote progress across digitization and connectivity, e-mobility, sustainable energy, digital health, and personalized care. Since I invested in the company in 2008, Exyte has exceeded all expectations and the company will again achieve record sales and results in 2022. I look forward to continuing to support Exyte's successful strategy and its future growth together with BDT."

Dr. Wolfgang Büchele, CEO of Exyte, says: "Our clear focus on high-tech industries is paying off. Due to the favorable market outlook and Exyte's focus on semiconductors and batteries, biopharma and life sciences, and data centers, we are well positioned in our markets and successfully on our "Pathway to Ten". This year, too, we will exceed our forecasts with targeted sales of around 7 billion euros, putting us closer to our goal of reaching 10 billion euros in sales in 2027. With our successful ongoing projects and significant project pipeline, we are well positioned for future profitable growth. I am pleased that BDT is convinced of Exyte's potential and prospects and will accompany us on our journey."

The closing of the transaction is subject to customary regulatory approvals. Financial terms were not disclosed. Deutsche Bank served as financial advisor to Exyte in connection with the transaction.

About Exyte

Exyte is a global leader in the design, engineering, and delivery of ultra-clean and sustainable facilities for high-tech industries. With cutting-edge expertise developed over more than a century, we serve clients in the sophisticated markets of semiconductors, battery cells, pharmaceuticals, biotechnology, and data centers. Exyte offers a full range of services from consulting to managing the implementation of turnkey solutions with the highest standards in safety and quality to our customers worldwide. We create a better future by enabling key industries to enhance the quality of modern life. In 2021, Exyte generated sales of EUR 4.9 billion with around 7,400 employees worldwide.

About BDT & Company

Established in 2009, BDT & Company is a merchant bank that provides advice and long-term capital through its affiliated funds to help family- and founder-led businesses pursue their strategic and financial objectives. The firm works with the owners and leaders of these closely held businesses to find creative solutions to their most complex issues, while also providing access to its world-class network. The firm's affiliate, BDT Capital Partners, has deployed more than $30 billion in capital through its investment funds and co-investments by its global investor base.

Contacts

ExyteRené Ziegler Vice President Corporate Communications & Investor Relations +49 711 88044606+49 172 5838786

[email protected] www.exyte.net

BDT & CompanySara Evans / Matthew Glasser(312) 529-6548 / (312) 385-2883

[email protected]

Logo - https://mma.prnewswire.com/media/1487100/Exyte_Logo.jpg

SOURCE Exyte

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Are there times when you create a document and have a saved file that would make a good reference? In Microsoft Word, you can embed a file and either link to it or display it as an icon. You can then pop open that document, spreadsheet, or media file with a simple click whenever you need to.

You might have a college paper where another paper you’ve written can provide insight or a business report where a financial PDF would help. Maybe you have an article where a media file would be ideal.

Whatever you’re creating, we’ll show you how to embed a file into a Word document using the steps below.

You can embed almost any file type into a Word document and display it as an icon or link. To do this, insert an object. Place your cursor in the document where you want to embed the file and follow these steps.

To show how the embedded file displays, here’s a screenshot with the same file as a link, an icon, and with neither Link to File nor Display as icon selected. Note that if you insert a link to the file, you may see a small icon for the file type or associated application.

To open the embedded file, double-click the icon or the link.

Some people also consider “embedding a file” as inserting the file’s contents into a document. We’ll explain how to insert text from another file in Word. Here’s how:

The contents of the file will appear in your Word document.

As you can see in the screenshot below, we inserted text from the file on the left into our document on the right.

You can easily embed a file in Word using the steps we’ve outlined above. This could be a media file containing audio or video or text from a PDF or a TXT text file. You can even embed PowerPoint slides into Word or add Excel data to your Word pages directly.

For more, take a look at how to follow hyperlinks in Word or how to insert an Excel table into word with VBA. Keep up with future tutorials by connecting with us on Twitter or Facebook!