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Conditions that cause both high and low MCHC values often result in similar symptoms. Since both high and low MCHC levels are correlated to difficulty transporting oxygen through your body, both can lead to serious fatigue. Since your body isn’t getting enough oxygen, your cells aren’t getting the energy they need and you feel tired.

Other symptoms of high and low MCHC include:

Since you’re not getting as much oxygen in your body, your body loses some of its ability to regulate your temperature. For many people with anemia and low or high MCHC levels, this means they often feel cold even when others around them feel comfortable.

If your MCHC values are low, then your heart will need to compensate to get more oxygen to the rest of your body. That can lead to a rapid heart rate even when you’re resting. You can also have a rapid heart rate with certain conditions that lead to high MCHC levels.

Your blood is partly responsible for the color of your skin, especially among paler people. Some people with different forms of anemia or other hemoglobin complications will appear pale or yellow because there is less blood to color their skin.

When your body is struggling to get enough oxygen, you may experience shortness of breath. This is common in more severe cases of anemia.

When your brain doesn’t get enough oxygen, you may feel dizzy or off-balance.

In severe cases, symptoms of anemia and high or low MCHC values can include:

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