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Table 1 Initial status.

The patient has all his health problems under control, except for his tendon pain, and he is a compliant patient after analyzing the criteria of the Morisky Green Test. He doesn't have any of the diseases described in the bibliography, and all of the drugs he is prescribed are within the prescribed ranges.

Olmesartan uses the OATP1B1 transporter for its metabolism, but also acts as an inhibitor of saidUbiquitin in 60.4%, as we observed the state of the situation.

This means that the metabolization of any drug that uses this sameprotein will be slowed down and the active drug will accumulate in the blood. The drugs prescribed for the patient use the same transporter protein to eliminate it. The effective dose of statin could be increased by the inhibition of OATP1B1 if this patient was prescribed the prescribed dose.

There are side effects of rosuvastatin, among them myalgia.

The appearance of adverse effects is related to the prescription of Olmesartan. Since the existence of other medical causes that justify it does not seem probable, we can determine a possible interaction between both drugs as the cause of the Achilles tendon injury.

The use of a statin is necessary for a patient with high cholesterol and high cardiovascular risk.

We decided to keep Rosuvastatin because it is the only statin that does not use the P-450 enzymes for metabolization and therefore the chances of interacting with other drugs in the patient's therapy is lower.

Since the patient doesn't suffer fromrenal failure, there is no risk of the active statin accumulating in the patient's blood and it would be the optimal drug for this patient.

We decided to reduce the dose of the drug because of the effect of the interaction on the blood values.

With all the above data, a report was made to the doctor, through a letter in an open envelope, via the pharmacist-patient-physician, where the doctor was informed of the possible interaction between Olmesartan and Rosuvastatin, and the appearance of the adverse effect caused by rosuvastatin, advising a decrease in the dose of rosuvastatin to 5 mg.

He was asked to have a second total cholesterol test 3 months after the dose change to make sure his total cholesterol values were still adequate.

The doctor called the patient 3 months later to repeat his total cholesterol analytical values after decreasing the statin dose to the values recommended by the pharmacy. The patient went to the pharmacy 60 days after the change in medication and told them that he was able to go up and down stairs without any problems.

The values continued to be optimal when the new analyses were performed.

The Naranjo Algorithm was used to estimate the probability of defining an adverse effect caused by a drug, and it yielded a value of 7.

A value of 8 points was obtained after the "Scale of Probability of Drug Interactions", which corresponds to the degree of probability of interaction between Olmesartan and Rosuvastatin. The Spanish Pharmacovigilance System of medicines for human use was notified through its website.

Due to the increased life expectancy of our patients and the high number of necessary medications prescribed per patient, the community pharmacist often finds himself unable to assess the patient's therapy effectively on a day to day basis. The study of the medication can be carried out in a fast and efficient way, using the same principles as the one described in the previous case, in which the prescribed doses are quickly evaluated.

The community pharmacy is a perfect place to establish a professional pharmaceutical care service due to its role in Primary Care.

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Here's what you need to know about stalkerware and how you can protect yourself from it.

Stalkerware refers to invasive programs installed on your computer or mobile device that enable the installer to spy on your online behaviors without your knowledge. A parent spying on their kid is the mildest form, but when it’s done secretly, without your child’s knowledge, it can erode trust and cause your kid to feel violated. The creepiest form it takes is with jealous exes, suspicious spouses or even your employer tracking everything you do.

Stalkerware can run secretly in the background on computers, phones and other handheld devices, collecting a slew of data for the spy to peruse. FlexiSPY (https://www.flexispy.com/) is the most common spy software, but it's certainly not the only one.

Think about how much you do on your phone: Texting, pictures, web searches, health and fitness tracking, etc. GPS location services on your phone can even allow a program like this to track where you are at all times. Scary stuff.

One reassuring note is that it's relatively difficult to install this sneaky software on someone's device. It typically requires physical access to the computer, phone or handheld device. While there are some rare cases where the software can be installed through a virus, like an infected link you click on in an email or on a website, this is a much less common infection method.

Despite the fact that stalkerware transmission via email or weblink is rare, you should be suspicious of links you receive through email or social media. We recommend never clicking on unsolicited links.

Think you may be infected? Here are some things to consider:

1. Has someone like a jealous ex, employer or suspicious spouse had un-monitored access to your phone or computer?

2. Have you noticed performance issues such as unusual slowness, crashes, programs glitching or your battery draining faster than usual?

On your computer, look for applications running in the background that you don't recognize. Windows users, right-click on the taskbar and choose Task Manager to see the list of programs currently running. Mac users, launch Activity Monitor from Spotlight. If you find any programs in the list that you don't recognize, do some research on what they are before you disable them, so you don't deactivate something that's critical to your computer's function.

Lock down any program accessing your webcam without your explicit permission. Windows users can go into Settings under Privacy and Camera and toggle off anything you don't approve of. Mac users can install a program called Oversight (https://objective-see.com/products/oversight.html). With it, you'll be notified whenever your Mac's microphone is activated and when any program accesses your webcam.

If you think it's possible that your mobile phone has been infected, there are a few things you can check. For iPhone users, most secret monitoring requires your phone to be “jailbroken.” Check your phone for an application called Cydia. If your iPhone is running an old version of iOS that cannot be updated, that could be an indication that your phone has been compromised.

Android users may have apps from unknown sources enabled. Under Settings --> Security, you can see whether  "unknown devices" has been toggled on.

To get rid of cell phone monitoring, the easiest way is to perform a factory reset on your phone. This will overwrite any jailbreak programs and reset all your security settings back to their original configuration. Just be aware that you'll lose all the data on your phone too, so make sure you back up your pictures and contacts before you do it.

On your computer, FlexiSPY can be eliminated using the FlexiKiller Tool (https://ops.securitywithoutborders.org/flexispy/). The website has explicit instructions about how to detect and remove it for both Windows and Mac users, so follow the directions carefully.

As always, you should be running up-to-date antivirus and anti-malware scanners. Windows users can utilize Microsoft Safety Scanner (https://www.microsoft.com/en-us/wdsi/products/scanner) to find and remove malware. It only scans when manually triggered, so install and run it if you think you may be infected.

More common than stalkerware is someone logging into your email or social media profiles without your permission. If you suspect this is happening, change your passwords immediately. Also change any accounts with the same password. Enable multi-factor authentication wherever it's available so that you will be automatically notified when someone tries to access your account from an unknown device.

Google users can see which computers and phones have recently accessed their Gmail account under Device Activity and Notifications here: https://myaccount.google.com/. Facebook users can check their active Facebook sessions under Settings at https://www.facebook.com/settings. Click on Security and Login at the upper left-hand corner of your screen. Once you see the list of "Where you're logged in," click on "See More" to see historical logins on your account. Click on the ... and log out of any active sessions that you don't recognize.