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Difference between Demat and trading Account is that a Demat Account holds the shares and securities (Bonds, ETFs, Mutual Fund units, etc.) in digital mode

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To carry out our experiment, we need a large text file. We will get this file from the UCSC download page. The hg38.FA.gz file is the one we will be using.

Don't worry if you don't understand the above statement, it's genetic-related terminology. The idea of reading large text files using Python is important in this lesson.

The file is 938 MB, so please be careful when you download it. You can use any of the tools listed.

You will get a file called hg38.FA after you have unzipped the file. To get a text file, change its name to hg38.

The traditional way to open a file is to use a word processor or text editor. Let's see what happens when we attempt that.

I tried to open the file using Microsoft Word, but it did not work.

The file could not be opened using WordPad and Notepad on a Windows based machine, but it could be opened using TextEdit on a Mac OS X machine.

It would be a good idea to have a way that would open such large files.

We'll see how to do it in this quick tip.

We are going to see how we can use Python to read our large file.

We wanted to read the first 500 lines of our large text file. We can simply do it.

The 500 lines of hg38.txt we read and write to a new text file output.txt should look like this.