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• Expect the best. Rather than worrying about the worst that can happen, we can expect God to bring us the best.
• Pray regularly. Communicating with God through prayer is an essential way to access both hope and joy.
• Look forward to learning as our future unfolds.

People should always speak with a doctor about medication for treating PE, as some pills for the condition may interact with other medications or existing health issues. Therefore, the safest option is to consult a medical professional for recommendations.

Some prescription and nonprescription pill medications that may help PE include:

Certain ED medications can also help treat PE.

These are called phosphodiesterase 5 (PDE5) inhibitors and include:

They work by affecting the enzymes in the penis and lungs to prolong erections and decrease pressure on the lungs, which calms down breathing.

Current research suggests that PDE5 inhibitors are effective in treating PE. However, these medications are more effective if a person takes them in combination with selective serotonin reuptake inhibitors (SSRIs).

The overall benefits of PDE5 inhibitors are similar to those of other medications and include better ejaculation control, confidence, and delayed ejaculation.

Side effects depend on the specific type of drug and may include:

People taking nitrate medications, such as nitroglycerin, should try to avoid taking PDE5 inhibitors due to a risk of a sharp decline in blood pressure.

Additionally, those looking to use off-label ED drugs, such as Viagra, must be aware of how they may interact with other medications.

For example, health experts warn that individuals should not combine the hypertension drug riociguat with ED medication.

All the above ED medications are available via prescription.

Learn more about ED medication.

The common use of antidepressant medication is to treat individuals with depression and anxiety.

However, several studies show that the off-label use of two antidepressants may help treat PE by delaying ejaculations.

These antidepressants are SSRIs and tricyclic antidepressants (TCAs).

An older 2016 study shows that ejaculation delay can increase within 10 days of taking the drug. However, individuals may need up to 3 weeks of treatment to achieve the maximum effect.

That study showed that the SSRI drug paroxetine was the most effective drug for delaying ejaculation.

However, there are a few concerns with antidepressant use:

The FDA also lists some medications that individuals cannot take with antidepressants, including monoamine oxidase (MAOI) inhibitors, thioridazine, and pimozide (Orap).

It also advises that individuals with narrow-angle glaucoma exercise caution when using SSRIs and TCAs.

Tramadol is an analgesic drug that reduces sensitivity to the receptors that produce serotonin.

An older study states that there are two types of serotonin: 5-HT(2C), which increases erections and stops ejaculation, and 5-HT(1A), which helps people reach ejaculation and can stop erections. The drug works by blocking this second type of serotonin.

A 2021 study shows that administering the drug hours before sexual intercourse resulted in higher intercourse satisfaction and reduced PE.

However, tramadol is only available with a prescription.

It is also an opioid, which carries concerns for drug dependency and misuse. Further research is necessary to understand the risk of opioid addiction from tramadol.

Individuals looking to take tramadol should be aware that the FDA warns of serious risks, including death if they combine this drug with benzodiazepines.

Learn more about tramadol.

Codeine is another type of analgesic drug.

A 2017 study shows one case where a person taking codeine saw improvements in controlling their ejaculations during intercourse.

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