Mukunda Sami

Anti-aging ingredients are some of the most important components people look for in their skincare products.

If you're looking to add anti-aging elements to your skincare routine are intimidated by Botox injections and get dried out by retinol, epidermal growth factors (EGFs) might be for you.

Typically found in high-end beauty products, EGFs were discovered in the 1950s by two Nobel-prize winning scientists as a way to speed up wound recovery and burns. It wasn't until the early 2000s that EGFs began making their way into skincare products, according to Allure.

Growth factors act as signals for the body to produce specific components of skin, like collagen, melanin, and keratin, Coveteur reported.

The EGFs found in beauty products are made using stem cells, which can help rejuvenate older skin cells.

"Research has been substantial on growth factors when it comes to reducing lines and wrinkles," Kim Chang, a licensed medical aesthetician, told Baylor College of Medicine. "They also work by adding hydration and decreasing tactile roughness in the skin."

Dr. Ioannis Liakas, medical director at Vie Aesthetics, told Refinery29 EGFs can also guard against the effects of pollution and sun damage, which both contribute to aging.

"I would say EGF is the ultimate ingredient for repair," Anna De La Cruz, an educational medical aesthetician, told Bustle.

Typically, EGFs can be found in hydrating products like serums, moisturizers, and creams.

Similar to retinol, products that contain EGFs help increase cell turnover to reduce skincare concerns like wrinkles, fine lines, and hyperpigmentation.

However, for people with sensitive skin, daily retinols can increase dryness, inflammation, or generally irritate the skin. EGFs can be more gentle on the skin than retinols, according to Liakas.

"If your skin is too sensitive to tolerate retinoids, then growth factors can be a substitute to stimulate collagen, even tone, and decrease roughness with much less irritation," dermatologist Dr. Hadley King told Coveteur.

But the benefits of EGFs do come as a cost, as they usually are only found in expensive, high-end beauty products.

The iPhone's design hasn't changed much over the years, but each time it does, Apple changes the role each button plays. For example, holding in the side button on the iPhone 11 and iPhone 12 doesn't prompt you to turn off your iPhone. Instead, it triggers Siri, which awaits your question or command a split-second later. I've received countless emails and DMs on Twitter asking for instructions detailing how to turn off the latest batch of iPhones.

You have to use a combination of buttons to turn off your phone now. And if you really can't remember which buttons to press and when, there's a software button buried in the settings app that turns off your phone.

Below I'll walk you through the mysterious button combination to turn your iPhone off, another button combo that will restart a problematic iPhone and, finally, where you can find the software button to turn it off.

So here's what you need to do to get the power menu to show up: On your iPhone 11 or iPhone 12, you'll need to press and hold the volume down button and the side button at the same time. It won't take long -- just a second or two. You'll feel a haptic vibration and then see the power slider on the top of your screen, as well as a Medical ID and an Emergency SOS slider near the bottom.

Slide the power switch from left to right and your phone will power off. To turn it back on, press and hold the side button until you see the Apple logo on the screen.

If your phone is running slow or is frozen and you can't get the power menu to show up, you can initiate a hard restart by using a button sequence Apple introduced with the iPhone X.

Start by pressing and releasing the volume up button, then press and release the volume down button. Finally, press and hold the side button. A new power menu will show up, forgoing all of the medical and emergency info. But instead of sliding the switch, keep holding the side button until you see the Apple logo appear on your phone.

Don't worry, a hard restart to your phone doesn't erase any data or information. But it does, more often than not, fix whatever issue you're experiencing.

If you just can't commit the button combination to memory, maybe this will be easier. Open the Settings app and go to General and scroll all the way to the bottom of the screen. There, you'll find a button labeled Shut Down. Tap it and slide the power off toggle to turn your phone off.

That wasn't too bad, was it? To be honest, I rarely turn my phone off. Instead, I mostly use a hard restart to power my phone off and back on automatically. Since it's my main troubleshooting method and no data is lost, it can't hurt.

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2. Tap Start Live Video
3. Tap at the bottom to invite friends or group members to watch your live video
4. You can also add a friend or group member who has requested to join your live video by tapping and tapping Approve next to their name

The guidance is in relation to players standing in an offside position when a free-kick is taken. “Professional Game Match Officials Limited (

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If you want some areas to be non-visible, try this one: I think that's closest to what you want (the example actually does the same thing you want, but it seems to be geared towards Canadians ;)).

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Instance methods take instance as first argument:

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You can also use @staticmethod decorator to create static function:

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Source: zaubee.com

• Rest in bed.
• Lie down so that your scrotum is elevated.
• Apply cold packs to your scrotum as tolerated.
• Wear an athletic supporter.
• Avoid lifting heavy objects.
• Avoid sexual intercourse until your infection has cleared.