Ask Sawal

Discussion Forum
Notification Icon1
Write Answer Icon
Add Question Icon

jocg Madan

Posted Questions

No Question(s) posted yet!

Posted Answers


  • Choose commerce or science in higher secondary.
  • Get bachelor's and master's degrees in economics.
  • Complete your doctorate.
  • Start working in a research centre.
  • Complete a certification course.
  • Develop your skills.
  • Choose your job specification.
  • Publish papers and books.

Answer is posted for the following question.

How to become an economist in imf?


Since the late 1980s, pharmaceutical manufacturers and contract manufacturing organizations (CMOs) have been familiar with occupational health categorization (OHC) systems. As a review, the OHC category assignment for an active pharmaceutical ingredient is determined by its inherent toxicity and potency, and the OHC category assignment is linked to the control band assignment that determines the engineering, administrative, and personal protective equipment needed to ensure safe handling.

While there are many different occupational health categorization schemes in common use, all occupational health categorization systems share a common feature - the higher the OHC band assignment the greater the requirement for rigorous control measures. In many cases, depending upon the risk assessment, active pharmaceutical ingredients with high OHC assignments will require the use of either flexible or rigid isolators to maintain occupational exposures and cross-contamination risks to an acceptable level, and in some cases, certain CMOs may not be able to handle your compound because they don’t have in place the proper controls and facilities.

In all commonly used OHC banding systems, Category 1 represents the least hazardous compounds, while Category 4 or 5 compounds (depending on the company-specific scheme) are considered highly potent and have the lowest acceptable occupational exposure levels and demand the greatest levels of engineering, administrative, and personal protective equipment.

GHS stands for the “Globally Harmonized System of Classification and Labelling of Chemicals” and has been a worldwide attempt to have a globally harmonized system for defining chemical hazard classifications, labeling systems (including standardized hazard symbols) and standardized safety data sheet formats. In the European Union (EU) the deadline for chemical classification was December 1st, 2010. In the United States of America (USA), since 2015, the use of the globally harmonized system (GHS) of classification and labeling of chemicals has been a regulatory requirement.

In the EU, GHS has been an integral part of the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) registration process, and in the USA, the Occupational Safety and Health Administration (OSHA) requires that GHS requirements be used for safety data sheet (SDS) preparation. As a result, in a GHS-compliant SDS, the GHS categorization for compounds can now be found in Section 2 on SDS. GHS is a short-hand method that describes the hazards of compounds according to precise regulatory definitions. For GHS health hazards, it does this by assigning a numeric “category” level for different toxicology endpoints for which data exist. Toxicology endpoints include things like acute oral toxicity (LD50), skin irritation, eye irritation, skin sensitization, genotoxicity, reproductive toxicity, carcinogenicity, etc. An example of how GHS hazard categorization would be used for acute oral toxicity (LD50) is shown in the table below. A compound with an LD50 of 25 mg/kg, e.g., would be a Cat 2, while a compound with an LD50 of 1800 mg/kg would be a Cat 4. Categorization schemes for other endpoints may differ somewhat, but use the same basic idea. In general, the lower the GHS numerical category the greater the hazard for that endpoint, while the higher the numerical category has a lower hazard. A special designation of NC (not classified) is provided for compounds that are determined not to show that specific hazard. In the LD50 case, it’s an LD50 greater than 2000 mg/kg.

The interesting observation is that the numeric categories for occupational health categorization bands and GHS categories go in opposite directions! A low classification number for an OHC band indicates the compound is less hazardous, while a low number for GHS classification indicates greater hazard. Similarly, a high number for an OHC band indicates greater hazard, while a high number for a GHS categorization indicates lower hazard.

As an example, the occupational toxicology experts from Affygility Solutions retrieved a safety data sheet for vitamin D3 (CAS RN 67-97-0), also known as cholecalciferol, from a reputable large pharmaceutical manufacturer. The information contained in the safety data sheet is as follows:

Occupational health categorization: 5 (the highest and most hazardous) Acute toxicity (rat, oral) LD50: 43 mg/kg, which corresponds to a GHS acute toxicity category 2 (moderate toxicity)

As a second example, we retrieved another safety data sheet from a different pharmaceutical manufacturer for a product containing acitretin (CAS RN 55079-83-9). The information contained in this safety data sheet was as follows:

Occupational health categorization: 4 (highest OHC category for this company and highly potent) Acute toxicity (rat, oral) LD50: >4,000 mg/kg, which corresponds to a GHS categorization assignment of NC (not classified, meaning not exhibiting toxicity for that endpoint)

As a third example, we retrieved another safety data sheet from a third pharmaceutical manufacturer for a product containing fentanyl citrate (CAS RN 990-73-8). The information contained in the safety data sheet was as follows:

Occupational health categorization: 5 (highest OHC category for this company, highly potent, and with a skin designation) Acute toxicity (rat, oral) LD50: 18 mg/kg, which corresponds to the GHS acute toxicity category of Category 2.

So, as you can see from the above three examples, without a proper understanding of the differences in the two categorization systems, it would be quite easy to get the two systems confused. And, to make matters worse, there are many safety data sheets on the internet that are poorly written and contain improper classifications.

Answer is posted for the following question.

What is ohc in chemistry?


By using a transistor to switch bigger loads, you can also automate the process of switching or switch ON or OFF the load remotely instead of

Answer is posted for the following question.

How to use bjt?


There are many reasons to use sva images.

Let's see how you can work with images in sva.

If you want to use the image in this example, you need to follow the steps below.

The image should be on your computer if you follow the steps correctly.

You can open the SVG image in your text editor. It could be renamed to happy.svg.

There are many ways to use sva images. We will explore six different methods in this video.

The easiest way to add sva images to a web page is through this method. To use this method, add the img> element to your document and reference it in the attribute.

You can add the above code snippets into your document if you downloaded the sg image from unDraw and renamed it happy.svg.

If you've done everything right, you should see the same page.

The size of the original SVG file is assumed when an sva image is added using the img> tag.

In the demo above, I didn't change the size of the image, so it assumed its original size.

To change the original size, you have to specify the width and height in the demo.

You can change the width and height directly.

If you want to make major style changes to the sva image, there are restrictions that need to be met.

This is similar to using the img> tag to add sveiwng to anhtml document. The following code snippets show us how we do it withCSS instead ofHTML.

The limitations to using img> when using an sva as a background image are the same as the limitations to using sva as a background image. It allows for a bit more personalization.

Feel free to make changes to the demo using theCSS.

The svg> /svg> tag can be used to write images into the document.

To do this, you need to open the sva image in your code, copy the code, and paste it into the sva element in your document.

If you've done everything right, your web page should look the same.

The loading time is reduced when the sg is used inline in the document.

The method allows you to do more customization than using img> or background-image.

You can use the following code to add sva images to a web page.

The data attribute is used to specify the URL of the resource to be used by the object, which in our case is a sva image.

The height and width are used to calculate the size of the image.

Answer is posted for the following question.

How to validate svg image?


Hearing loss caused by damage to the inner ear or the nerve from the ear to the brain.

Answer is posted for the following question.

Who sensorineural hearing loss?


Description Woodward's Stores Ltd. was a department store chain that operated in Alberta and British Columbia, Canada, for 101 years, before its sale to the Hudson's Bay Company. Wikipedia

Answer is posted for the following question.

When did woodwards close?


Description Stirling is a city in central Scotland. At the heart of its old town, medieval Stirling Castle is on a craggy volcanic rock. On the Abbey Craig outcrop, the National Wallace Monument is a 19th-century tower. It overlooks the site of the 1297 Battle of Stirling Bridge, where William Wallace defeated the English. The Battle of Bannockburn Experience has interactive 3D displays on the history of the 1314 conflict. ― Google

Answer is posted for the following question.

Stirling what does that mean?


Main usage of Asmazed 50 mg/1.25 mg/4 mg Syrup is for Cough with mucus.

Asmazed 50 mg/1.25 mg/4 mg Syrup

Asmazed 50 mg/1.25 mg/4 mg Syrup helps to loosen thick mucus, making it easier to cough out. This makes it easier for air to move in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours.
Take Asmazed 50 mg/1.25 mg/4 mg Syrup as prescribed by the doctor. Do not stop using it unless you are advised to by your doctor. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms.

Answer is posted for the following question.

Why Asmazed 50 mg/1.25 mg/4 mg Syrup is used?