In English, 'skunk' has become slang for any potent, high-THC strain of cannabis. When media in the United Kingdom speak about skunk, they mean all high-THC cannabis varieties, regardless of their genetic heritage. There, skunk doesn't refer to the aroma of particular strains of marijuana. Skunk weed may refer to: Skunk (cannabis), a selection of selectively bred cannabis strains, scent comes from naturally occurring acids that are reminiscent of.