Dua Wentzle

To get MK2 weapons in GTA Online, you need a Weapon Workshop. This can be added to three types of properties:

1. A Mobile Operations Center (MOC) with the Weapon & Vehicle Workshop bay (requires a Bunker to store the MOC). 2. An Avenger with a Weapon Workshop in its facilities. 3. An Arena Workshop with the Weapon Expert mechanic.

Once you have one of these, you can take a base weapon (like the Carbine Rifle) to the workshop and pay to upgrade it to its MK2 version. However, the customizations (like special ammo: incendiary, armor-piercing, etc.) are locked behind Research.

Research is done exclusively in your Bunker. You need to own a Bunker (like Farmhouse or Chumash), upgrade its Equipment and Staff, and then assign your staff to "Research" in the Bunker's computer. Research is random and unlocks things for MK2 weapons, vehicle weapons, and some vehicle modifications. You can fast-track research projects with GTA$, but it's expensive. So yes, you technically need a Bunker to unlock all the good stuff for your MK2 weapons, and one of the workshop properties to actually create and customize them.

In the lab, we do this routinely for RNA-seq prep. Ribosomal RNA (rRNA) can make up >80% of total RNA, so removing it is crucial for sequencing non-coding RNA or mRNA. The gold standard method is using commercial kit-based depletion. Kits like Illumina's Ribo-Zero Plus, QIAGEN's FastSelect, or NEB's rRNA Depletion Kit use biotinylated probes that hybridize specifically to rRNA sequences (both cytoplasmic and mitochondrial) in your sample. You then mix it with magnetic beads that bind to the biotin, and pull down the beads with a magnet. The supernatant contains your rRNA-depleted RNA (the "clean" RNA), which you then precipitate and clean up. It's efficient and reliable for most eukaryotic samples. Always check the kit's compatibility with your organism (human, mouse, rat, bacteria, etc.).