Antiphospholipid antibodies are a group of immune proteins (antibodies) that the body mistakenly produces against itself in an autoimmune response to phospholipids. To identify APLA, the laboratory tests include enzyme-linked immunosorbent assay (ELISA), and functional assays. The two most common types of antiphospholipid antibodies are lupus anticoagulant and anticardiolipin antibodies. APL or antiphospholipid antibody test is performed to diagnose antiphospholipid syndrome, where the antibodies attack body's own tissues by. ELISA is the test used to detect these antibodies, IgM and IgG isotypes. LA is considered positive when two of the following three tests [hexagonal neutraliza- tion test (StaClot LA 20, Diagnostica Stago, Asnie`res,.