Guava (/ˈɡwɑːvə/) is a common tropical fruit cultivated in many tropical and subtropical regions. 8 Health Benefits of Guava Fruit and Leaves · 1. Guava is a tropical fruit native to Mexico, Central America, the Caribbean, and South America. Undeniably, it is one fruit which always got enough lauding from our grandmothers. What Is Guava? Guava is a tropical fruit typically grown in Mexico, the Caribbean, and parts of Central and South America.