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In inorganic chemistry, bicarbonate is an intermediate form in the deprotonation of carbonic acid. Bicarbonate is the second largest fraction of the anions in plasma. Bicarbonate, also known as HCO3, is a byproduct of your body's metabolism. Bicarbonate Ion is a polyatomic ion whose formula is HCO3-. clinical definition of bicarbonate (hco3-). What is an Arterial Blood Gas (ABG)?.