Hypochlorous acid is a weak acid that forms when chlorine dissolves in water, and itself partially dissociates, forming hypochlorite, ClO⁻. Hypochlorous acid is considered nature's germ killer. Hypochlorous acid (HOCL) is the most effective disinfectant in the chlorine family available in dilute solution. How is hypochlorous acid made? To make hypochlorous acid is pretty simple chemistry. Objective: Hypochlorous acid (HOCl), a major inorganic bactericidal compound of innate immunity, is effective against a broad range of.