The Blood Safety and Quality (amendment) Regulations 2006/2013 further amend the BSQR 2005 (SI 2005/50) ("the principal regulations") to make a number of changes to the provisions governing the operation of blood establishments (establishments which collect, process and test human blood and blood components) and. The Regulations implement the provisions of Directive 2002/98/EC and associated Directives so that the retention periods for data relating to human. November 2005 and in subsequent years, and that MHRA use a standard format for compliance reporting and publish criteria for any intended compliance. These Regulations impose safety and quality requirements on human blood collection and storage. (2) Except for regulation 25(1), which shall come into force on 8th November 2005, these. To help facilitate compliance with the BSQR (2005), the requirements of a quality management system will be included as part of workload and service delivery.