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Why thrombocytopenia in dengue?

2 Answer(s) Available
Answer # 1 #

Thrombocytopenia in dengue may arise either from decreased production of cells from the bone marrow or from increased peripheral destruction of platelets and clearance from peripheral blood. A high mean platelet volume (MPV) indicates enhanced platelet destruction in patients.

Shafiq Rimsha
Answer # 2 #

It must be noted that all four of them can potentially cause dengue fever. The term 'dengue fever' is frequently used to distinguish clinically milder dengue virus infections. In more severe cases, however, the term 'dengue hemorrhagic fever (DHF)' is used.

One of the common complications of dengue fever is a decrease in the number of platelets in the blood, which is called thrombocytopenia. The decrease in platelet count in dengue fever is believed to be due to the destruction of platelets by the dengue virus. The virus infects and damages the bone marrow, where platelets are produced, leading to a decrease in their production. Sometimes the immune system may also produce antibodies that attack and destroy platelets.

Dengue is a disease that can indiscriminately affect people belonging to all genders as well as age groups. The disease is also referred to as 'break-bone fever,' mainly because of the excruciating pain it may cause. It is prevalent all over the tropical and subtropical areas of the world, with about 50 to 100 million cases of dengue fever in more than 100 countries.

Among the common symptoms of dengue are fever, severe headache, pain in the eyes and joints, muscle and bone pain, rash, and fatigue. It usually gets better on its own, but occasionally can be fatal.

It is a viral disease transmitted by day-biting mosquitoes and is a major public health problem in many tropical and subtropical countries, with India, Brazil, and the Philippines being the top three countries.

Anyone who lives in or travels to the areas where dengue is present is at risk of being infected. However, certain groups of people may be more vulnerable to severe illness, including:

Dengue, in most cases, does not cause complications and has a self-limiting course with full recovery in two to seven days. However, it can also lead to the patient's demise in some cases.

As we already know, it is a mosquito-borne disease that may cause blood clots and impair blood coagulation. These blood clots can usually form in the patient's capillaries. However, at times, they can also form outside the blood vessels and block blood circulation to different parts of the body. These blood clots can cause the patient to feel faint and develop different grave complications.

This serious medical condition is caused by a virus that invades and damages the body's platelets, which are cell fragments that help blood clot. Dengue, or break-bone fever, causes the platelet count to decrease because the virus that causes platelet damage mainly affects the blood cells of the sufferer.

The platelet count in dengue fever is also one of the useful diagnostic tools and is usually carried out in cases in which the patient exhibits bleeding tendencies or has had recent trauma.

You should also note that the virus responsible for dengue fever is also responsible for another viral disease called yellow fever. All people affected by the dengue virus have similar symptoms and causes, but different amounts of blood damage. Blood damage is one of the causes of death in dengue fever.

A sudden dip in the platelet count is one of the primary reasons for blood loss in dengue; hence it has been given the name hemorrhagic fever. Moreover, platelets are a type of cell that allows the blood to clot when wounded and also helps in reducing bleeding.

When we get infected with a virus, the body goes into self-defense mode and starts to attack the virus. It is when the body releases white blood cells to look for the virus and destroy it. The platelets are responsible for clotting the blood, and when the platelet count decreases, then you have problems with the clotting of blood.

This is usually the reason that people get seriously injured and enfeebled by dengue fever. A severe infection can lead to bleeding from the mouth and nose, as well as internal hemorrhage.

During a season of dengue fever, people usually try to increase their platelet counts so that they have a better chance of fighting the infection. To do this, it is important to increase your consumption of foods rich in omega-3, vitamins, iron, and other minerals. These foods can help fight antibodies and also increase platelet counts in dengue.

You can also add kale and other leafy greens such as mustard greens, collard greens, turnip greens, and spinach to your meals. The thing about these leafy greens is that they are low in calories and high in vitamins A, C, and K, which are essential to combating the dengue virus. Also, the pigments present in these leafy greens are known to have great anti-inflammatory effects.

Deb Waldron
Chief Revenue Officer